From Tampa, Florida - 

To the resounding cheers of Republican delegates gathered in Tampa, Rep. Paul Ryan (R-WI) thrilled GOP delegates as he accepted his party's nomination, urging Americans to again vote for change in the White House to help improve the nation's economic fortunes.

"Why would the next four years be any different from the first four years?" Ryan asked to loud applause in Tampa, Florida.

It was by far the biggest speech of Ryan's political career, and he seemed more than ready for it, much to the delight of thousands of Republicans who hope victory is in their future this November.

"After four years of getting the run-around, America needs a turnaround, and the man for the job is Governor Mitt Romney," said Ryan.

Ryan repeatedly skewered the White House for trying to shift the blame on economic issues, accusing the Obama campaign of running a lowest common denominator bid for re-election.

"They’ve run out of ideas. Their moment came and went. Fear and division are all they’ve got left," said Ryan to more cheers.

One line that really had GOP partisans slapping their thighs in delight was where Ryan blasted the President over continuing economic problems, making the argument to young people that they should think about voting Republican in 2012.

"College graduates should not have to live out their 20s in their childhood bedrooms, staring up at fading Obama posters and wondering when they can move out and get going with life," Ryan said to cheers, as Twitter lit up with the hashtag of #FadingObamaPosters almost immediately.

Ryan started off by introducing his family to delegates - and more importantly - to the nation, and the kids didn't disappoint, drawing smiles as they waved to the assembled crowd.

At one point, Ryan even joked about the generational difference between himself and Romney, boiling it down to what was on their Ipods.

"I hope it’s not a deal-breaker Mitt, but my playlist starts with AC/DC, and ends with Zeppelin," Ryan said about what music he wanted to play at his campaign events. 

Now the stage is set for Mitt Romney. Will he deliver like his running mate?